Correction to: Detecting focal cortical dysplasia lesions from FLAIR-negative images based on cortical thickness

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Automatic Delineation of Focal Cortical Dysplasia Lesions on MRI

Rationale: MRI has allowed the recognition of focal cortical dysplasia (FCD) in an increasing number of patients. The precise delineation of FCD is important since freedom from seizures after surgery is closely related to the extent of resection of the pathological tissue. FCD lesions are difficult to delineate on MRI due to their ill-defined boundaries and the complexity of the cortex. We prev...

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Focal cortical dysplasia – review

Focal cortical dysplasia is a malformation of cortical development, which is the most common cause of medically refractory epilepsy in the pediatric population and the second/third most common etiology of medically intractable seizures in adults.Both genetic and acquired factors are involved in the pathogenesis of cortical dysplasia. Numerous classifications of the complex structural abnormalit...

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Focal Cortical Dysplasia.

Focal cortical dysplasias are common malformations of cerebral cortical development and are highly associated with medically intractable epilepsy. They have been classified into neuropathological subtypes (type Ia, Ib, IIa, IIb, and III) based on the severity of cytoarchitectural disruption--tangential or radial dispersion, or loss of laminar structure--and the presence of unique cells types su...

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Cortical development and focal cortical dysplasia.

A brief survey of cortical development is presented, focusing on neuronal migration and its alterations. Corticogenesis is achieved through ordered temporospatial steps, via the formation of transient structures, and successive waves of cell proliferation and migration (followed by cell differentiation and maturation), and apoptotic cell death. The appearance of the proliferative ventricular zo...

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Measuring Cortical Thickness in Brain MRI Volumes to Detect Focal Cortical Dysplasia

Nowadays the prevalence of epilepsy is estimated to be around 1% of the population where up to 40% of the patients continue to have seizures despite optimal drug treatment [1]. In patients with drug refractory epilepsy, approximately one-half suffer from localized malformation of cortical development known as focal cortical dysplasia (FCD). There, the epilepsy surgery can yield a high chance of...

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ژورنال

عنوان ژورنال: BioMedical Engineering OnLine

سال: 2020

ISSN: 1475-925X

DOI: 10.1186/s12938-020-00760-9